Two political activists and a woman were among 13 people killed in a fresh spree of targeted killing in the city on Wednesday, police said.
Two people were gunned down in an attack at a tea shop in Block M North Nazimabad by unidentified armed men.
Taimuria police said two men on a motorcycle targeted people sitting at Quetta Bolan Hotel.
The victims were shifted to Abbasi Shaheed Hospital, where they were identified as Sanobar Khan and Latif.
Sindh Home Minister has ordered closure of tea shops in city before 11 pm following the regular incidents of firing.
A man was shot dead and two others injured when unidentified bike riders opened fire at Baloch Hotel in Block 16, Gulistan-e-Jauhar.
Police said the victims were shifted to Jinnah Postgraduate Medical Centre (JPMC). The deceased was identified as 36-year-old Shafiullah.
In early hours of Wednesday, two bullet-riddled bodies of youth were found in gunny bags near the Karachi Medical and Dental College in North Nazimabad.
Taimuria SHO said the deceased appeared Pakhtun from physical appearance but their identity could not be ascertained.
Another dead body bearing torture marks was recovered from North Karachi Sector 5-J.
Bilal Colony SHO said the victim was identified as Rehan, 36 but the reason behind his murder could not be established.
The body of 40-year-old Amanullah was recovered from Karimabad Ghosht Market.
Azizabad DO said the victim was a resident of Chakiwara, Lyari and an activist of Pakistan Peoples Party (PPP).
A 28-year-old man was shot dead in No 8, Liaquatabad.
Liaquatabad police said the victim said to be activist of Mohajir Qaumi Movement-Haqiqi (MQM-H).
The body of a 40-year-old woman was recovered from a garbage dump near Al-Asif Square. Sohrab Goth police said the woman was identified as Yasmeen, wife of Ajab Khan.
Another man was killed near Lal School in Ghas Mandi.
Garden SHO said the victim was identified as Zohaib, 25, son of Abdul Qadir.
A 40-year-old man, identified as Imam Bux, was gunned down at Bakra Piri Road, Lyari in the jurisdiction of Kalakot police station.
Another man, identified as Zaraq Gul, was shot dead near the KMC View Apartments in the limits of Sachal police station.
A 35-year-old man was gunned down near Bakri Pump in the Surjani Town Sector L-1.
Surjani SHO said the victim was identified as Nadeem, son of Abdul Hameed, and said to be correspondent of a newspaper.