Top seed Kirsten Flipkins was dumped out of the AEGON Classic in Edgbaston in the third round by Slovakian Magdalena Rybarikova.
The 16th seed, the world number 47, claimed a 7-6 (7/5) 6-2 win over the Belgian in one hour and 24 minutes.
Third-seeded Romanian Sorana Cirstea survived a scare to progress as she saw off 13th-seeded Bojana Jovanovski of Serbia 6-1 1-6 6-1.
Sabine Lisicki, the fifth seed from Germany, was also taken to three sets by Croatia’s Mirjana Lucic-Baroni before coming through 7-5 2-6 6-4.
But her compatriot, the sixth-seeded Mona Barthel, crashed out, going down 6-3 6-2 to American Madison Keys.
French 12th seed Kristina Mladenovic also went out after losing 3-6 7-6 (8/6) 6-4 to Daniela Hantuchova of Slovakia.
Other winners today included 15th seed Francesca Schiavone of Italy and American pair Alison Riske and Maria Sanchez.
