Real Madrid has vetoed a £52.4m (€60m) bid for striker Alvaro Morata from Manchester United.
United goalkeeper David de Gea was not comprised in the offer, while Real Madrid is thought to want in the region of £78m for the forward.
The Spain international scored 20 goals in all contests for Real last season, as the club clinched La Liga and the Champions League.
If Manchester United fail to agree a deal for Morata, it is understood they will try to sign Andrea Belotti from Torino, who has a €100m (£87.3m) release clause in his contract.
Born in Madrid, Morata progressed through the Real Madrid academy to make his first team debut in December 2010, before exiting for Juventus in the summer of 2014 for £17.5m.
In two seasons with Juventus, Morata won two Serie A titles, two Coppa Italia titles and was part of a run to the 2015 Champions League final, scoring as Juve lost 3-1 to Barcelona.
In June 2016, Real Madrid exercised a buy-back clause to bring Morata back from Juventus for £26.2m, and the forward has emerged as a key member of Zinedine Zidane’s squad.