Three people were killed and one was injured in a US drone attack in North Waziristan on Monday.
Sources said missiles were fired at a residential compound in Char Khel area of Boya, a region close to the Afghan border.
Witnesses said the spy aircraft were still hovering over the targeted area spreading fear among the locals.
The victims could not be identified so far.
Only on Sunday, drone strikes killed four men in Darga Mandi area of the same agency.
US spy aircraft have been consistently targeting North Waziristan and a large number of people has been killed in these attacks since the beginning of the year.
Pakistan has been opposing drone attacks in its territory and raised the issue at the ongoing UN General Assembly session.